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X. Chris Le

Published in  2018-04-18 14:59:31       

  X. Chris Le, PhD, FRS(C), FCIC, FRSC(UK)
  Professor of Analytical Chemistry and Environmental Toxicology
  Faculty of Medicine & Dentistry
  University of Alberta
  Edmonton, Alberta, Canada
  Email: xc.le@ualberta.ca     

Talk title: Arsenic binding to proteins: chemistry and implications
Dr. Le is Distinguished University Professor, jointly appointed in the Departments of Laboratory Medicine and Pathology, Chemistry, and Public Health Sciences, and is the Director of Analytical and Environmental Toxicology Division. 

Dr. Le is an elected Fellow of the Royal Society of Canada (Canadian National Academy of Science), Fellow of the Royal Society of Chemistry (UK), and Fellow of the Chemical Institute of Canada. He has held an inaugural Canada Research Chair in Bio-Analytical Technology and Environmental Health for seventeen years. 

Dr. Le received BSc in Chemistry from Wuhan University (China), MSc in Environmental Chemistry from Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, MSc in Analytical Chemistry from Brock University (Canada), and PhD in Environmental/Analytical Chemistry from the University of British Columbia (Canada). 

Dr. Le’s research on arsenic deals with analytical techniques for arsenic speciation, assessment of human exposure to arsenic species, understanding of arsenic metabolism, and studies of arsenic interaction with proteins. Dr. Le has co-authored 250 peer-refereed papers, 22 book chapters, and 20 commentaries. He holds 10 United States patents.  

Dr. Le’s collaboration with more than 20 groups around the world has advanced (1) identification and determination of arsenic species, (2) understanding environmental and health effects of arsenic species, (3) studies of DNA damage and repair, (4) ultrasensitive detection of specific proteins, and (5) design of DNA nanomachines for live cell imaging.

Dr. Le has mentored 80 graduate students and postdoctoral fellows. Twenty-five (25) of his trainees currently hold independent academic positions in Canada, China, and the United States.